Research and analysis

Table 3b Preterm Birth

Updated 7 January 2021
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Table 3b Preterm Birth
Preterm Birth Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Carbamazepine Gabapentin Lamotrigine Levetiracetam Oxcarbazepine Phenobarbital Phenytoin Pregabalin Topiramate Valproate Zonisamide
Meta-analyses Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Veroniki et al 2017a OR 1.10 OR 1.93 (0.88,4.05) OR 1.05 OR 0.87 OR 0.80 OR 1.59 OR 1.03 (0.55,1.82) - OR 1.38 (0.73, 2.35) OR 0.96 (0.65,1.37) -
Not set (0.77,1.56) Not set (0.70,1.48) (0.04,8.14) (0.5,1.26) (0.87,2.75) Not set Not set Not set Not set Not set
Not set Not set N=76 Not set Not set Not set Not set N=283 Not set N=408 N=1694 Not set
Not set N=2141 Not set N=3015 N=93 N=1045 N=206 Not set Not set Not set Not set Not set
Pregnancy Registries Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
?Hernandez-Diaz et al 2014 - - 5.90% - - - - - 10.40% - 10.20%
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set N=1581 Not set Not set Not set Not set Not set N=347 Not set N=98
Birth Registers Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Margulis et al 2019 -1.3 (95 % CI -2.3 to -0.3) use any time - ref -0.5 (95 % CI -2.6 to 1.6) any time - - - -1.1 (95 % CI -3.0 to 0.8) any time - -0.0 (95 % CI -1.2 to -1.2) any time -
Swedish N= 1975 Not set Not set N=213 Not set Not set Not set N=522 Not set N=985 Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Mean pregnancy duration days compared with LMT -1.6 (95% CI -2.7 to -0.5) 1st trimester Not set Not set -0.7 (95% CI -2.9 to -1.5) 1st trimester Not set Not set Not set -1.8 (95% CI -3.7 to 0.2) 1st trimester Not set -0.1 (95% CI -1.3 to -1.2) 1st trimester Not set
Not set N=1686 Not set Not set N=184 Not set Not set Not set N=484 Not set N=845 Not set
Danielsson et al 2019 10.60% - 5.70% 7.20% - - - - - 4.50% -
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set N=243 Not set N=437 N=118 Not set Not set Not set Not set Not set N=130 Not set
Killic et al 2014 8.4% (all) 12.1% (all) 9.3% (all) 5.6% (all) 6.2% (all) 10.8% (all) - 22.2% (all) 4.7% (all) 7.6% (all) 0
Not set 8.1% (mono) 12.5% (mono) 9.4% (mono) 3.8% (mono) 6.5% (mono) 10.4% (mono) Not set 23.1% (mono) 8.5% (mono) 6.7% (mono) Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set N=416 N=91 N=1157 N=72 N=405 N=111 Not set N=18 N=129 N=461 Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
?Artama et al 2013 7.5% (all) - 4.3% (all) 10.7% (all) 4.6% (all) - 7.5% (all) - - 5.7% (all) -
Finland 7.7% (mono) Not set 4.6% (mono) 15.4% (mono) 4.4% (mono) Not set 7.7% (mono) Not set Not set 5.7% (mono) Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set N=1292 Not set N=345 N=56 N=695 Not set N=53 Not set Not set N=944 Not set
Not set N=1084 mono Not set N=173 mono N=13 mono N=532 mono Not set N=26 mono Not set Not set N=706 mono Not set
Fujii et al 2013 Not set 10.50% Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set N=223 Not set Not set Not set Not set Not set Not set Not set Not set Not set
Others Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Mostacci et al 2017 - 54.50% - - - - - 25% - - -
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set N=11 Not set Not set Not set Not set Not set N=16 Not set Not set Not set
Winterfeld et al 2016 Not set Not set Not set Not set Not set Not set Not set 9.20% Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set N=119 Not set Not set Not set
Ornoy et al 2008 - Not set Not set Not set Not set Not set Not set Not set 9.80% Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set N=29 Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set
Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set Not set